Protein Details: Aquaporin Z
Protein ID
ICDB_Pro_1152
Protein Name
Aquaporin Z
Gene Name
aqpZ; plu2033
Organism
Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) (Photorhabdus luminescens subsp. laumondii)
Length
231 amino acids
AlphaFoldDB
AF-Q7N5C1-F1-model_v4.pdb
Function
Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
Sequence
MLRKLAAELLGTFVLVFGGCGSVVFAAAFPELGIGFVGVSLAFGLTVLTMIYAVGHISGGHFNPAVTIGLWAGGRFRAVEVIPYIISQVIGGILAAAVLYVIASGQVGFDATTSGFASNGFGEHSPGGFSLQSAIVAEIVLTAIFLIVIIGATDRRAPPGFAPLAIGLALVLINLISIPITNTSVNPARSTAVAIFQNTWALEQLWFFWVMPIIGGIVGGGIYRLLFAEKQ
PDB Structures
Ligand Binding
Binding Site
SITE 20: "Involved in tetramerization or stability of the tetramer"; SITE 43: "Selectivity filter"; SITE 183: "Selectivity filter"; SITE 189: "Selectivity filter"
Disease
Location
DOI ID
10.1038/nbt886
RefSeq
WP_011146289.1